Damage to the anterior arcuate fasciculus predicts non-fluent speech production in aphasia

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Damage to the anterior arcuate fasciculus predicts non-fluent speech production in aphasia.

Non-fluent aphasia implies a relatively straightforward neurological condition characterized by limited speech output. However, it is an umbrella term for different underlying impairments affecting speech production. Several studies have sought the critical lesion location that gives rise to non-fluent aphasia. The results have been mixed but typically implicate anterior cortical regions such a...

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Speech errors in progressive non-fluent aphasia.

The nature and frequency of speech production errors in neurodegenerative disease have not previously been precisely quantified. In the present study, 16 patients with a progressive form of non-fluent aphasia (PNFA) were asked to tell a story from a wordless children's picture book. Errors in production were classified as either phonemic, involving language-based deformations that nevertheless ...

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The role of the arcuate fasciculus in conduction aphasia.

In aphasia literature, it has been considered that a speech repetition defect represents the main constituent of conduction aphasia. Conduction aphasia has frequently been interpreted as a language impairment due to lesions of the arcuate fasciculus (AF) that disconnect receptive language areas from expressive ones. Modern neuroradiological studies suggest that the AF connects posterior recepti...

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Relation between aphasia and arcuate fasciculus in chronic stroke patients

BACKGROUND The role of the arcuate fasciculus (AF) in the dominant hemisphere in stroke patients with aphasia has not been clearly elucidated. We investigated the relation between language function and diffusion tensor tractography (DTT) findings for the left AF in chronic stroke patients with aphasia. METHOD Twenty five consecutive right-handed stroke patients with aphasia following lesions ...

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Correlation between Brain Lesion Site and Fluent/Non-Fluent Aphasia

 Background and purpose: Aphasia is the most common communication disorder resulting from stroke. In this condition all modalities of language, including reading, writing, auditory perception, and oral speech may be affected. Aphasia is divided into two categories: fluent (Wernicke's aphasia, Transcortical sensory aphasia, conduction aphasia, and anomic aphasia) and non-fluent (Broca's aphasia,...

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ژورنال

عنوان ژورنال: Brain

سال: 2013

ISSN: 1460-2156,0006-8950

DOI: 10.1093/brain/awt267